Анализ крови с помощью телефона
07.06.2005
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Исследователи из шведского города Упсала (Uppsala) разработали портативную лабораторию, позволяющую пользователям мобильных телефонов производить быстрый и точный экспресс-анализ взятых образцов крови. Одноразовый микрофлюидный чип способен анализировать образцы крови, идентифицировать воспалительные процессы, устанавливать необходимость применения антибиотиков и возможный риск заболеваний сердца.
Будучи подключенным к телефону, чип измеряет биомаркеры, такие как CRP, тропонин I, тропонин T или BNP, содержащиеся в анализируемой крови. Миниатюрная помпа, расширяющаяся разогреваемым парафином, питается от батареи мобильного телефона и закачивает образец крови в специальные трубки, фильтры и камеры для реакций, используемые чипом.
http://www.hpc.ru
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Blood tests on a cellphone
Researchers in Uppsala, Sweden, are developing a portable laboratory that enables mobile phone users to conduct a quick and accurate analysis of blood samples. A disposable microfluidic chip that is able to analyse blood samples and thereby identify inflammatory conditions, the need for antibiotics and the risk of heart disease.
Attached to the phone, the chip measures quantities of specific biomarkers such as CRP, Troponin I or T, and BNP in blood samples. A micro pump, which is based on paraffin expansion and powered by the mobile phone battery, pushes the sample through channels, filters and the reaction chamber on the chip.
A camera then reads the tests results as light signals off the chip. This process is based on bioluminescence, which is the same chemical reaction that makes fireflies glow. After only a few minutes the results can be sent to a doctor, over a mobile phone network or the Internet. The only additional equipment the micro laboratory needs is a mobile phone with a digital camera.
Between five and ten million CRP-tests are conducted every year in Sweden alone. The Uppsala researchers aim to enhance the chip's functionalities even further in order to allow the conduction of several parallel blood analyses. The new bioanalytical microchip test is a time and cost efficient alternative to common blood tests, which costs about US$27 million per year in Sweden.
"The finalized chip has the potential to respond to any biomarker for which there is an existing antibody", says Jonas Åström, Project Manager for Uppsala BIO-X. "For future versions we want to increase the variety of tests that the chip can conduct."
The cross-disciplinary project includes researchers from Uppsala University, Mälardalens University College and the University Hospital. It received a ?661.000 grant from Uppsala BIO-X, an initiative for cross-disciplinary research.
"The chip builds up on different technologies, which we already have, but need to integrate", says Uppsala University's Lars Baltzer, who is head of the project. "This is where the different skills of our team come in handy", he explains further.
www.cellular-news.com/
Будучи подключенным к телефону, чип измеряет биомаркеры, такие как CRP, тропонин I, тропонин T или BNP, содержащиеся в анализируемой крови. Миниатюрная помпа, расширяющаяся разогреваемым парафином, питается от батареи мобильного телефона и закачивает образец крови в специальные трубки, фильтры и камеры для реакций, используемые чипом.
http://www.hpc.ru
-----------------------------------
Blood tests on a cellphone
Researchers in Uppsala, Sweden, are developing a portable laboratory that enables mobile phone users to conduct a quick and accurate analysis of blood samples. A disposable microfluidic chip that is able to analyse blood samples and thereby identify inflammatory conditions, the need for antibiotics and the risk of heart disease.
Attached to the phone, the chip measures quantities of specific biomarkers such as CRP, Troponin I or T, and BNP in blood samples. A micro pump, which is based on paraffin expansion and powered by the mobile phone battery, pushes the sample through channels, filters and the reaction chamber on the chip.
A camera then reads the tests results as light signals off the chip. This process is based on bioluminescence, which is the same chemical reaction that makes fireflies glow. After only a few minutes the results can be sent to a doctor, over a mobile phone network or the Internet. The only additional equipment the micro laboratory needs is a mobile phone with a digital camera.
Between five and ten million CRP-tests are conducted every year in Sweden alone. The Uppsala researchers aim to enhance the chip's functionalities even further in order to allow the conduction of several parallel blood analyses. The new bioanalytical microchip test is a time and cost efficient alternative to common blood tests, which costs about US$27 million per year in Sweden.
"The finalized chip has the potential to respond to any biomarker for which there is an existing antibody", says Jonas Åström, Project Manager for Uppsala BIO-X. "For future versions we want to increase the variety of tests that the chip can conduct."
The cross-disciplinary project includes researchers from Uppsala University, Mälardalens University College and the University Hospital. It received a ?661.000 grant from Uppsala BIO-X, an initiative for cross-disciplinary research.
"The chip builds up on different technologies, which we already have, but need to integrate", says Uppsala University's Lars Baltzer, who is head of the project. "This is where the different skills of our team come in handy", he explains further.
www.cellular-news.com/
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